Article
Generation and initial characterization of the prolactin-inducible protein (PIP) null mouse: accompanying global changes in gene expression in the submandibular gland.
Canadian journal of physiology and pharmacology - 1 Oct 2009
Blanchard A, Nistor A, Castaneda F E, Martin D, Hicks G G, Amara F, Shiu R P C, Myal Y
Abstract excerpt
The human prolactin-inducible protein/gross cystic disease fluid protein-15 (hPIP/GCDFP-15) is a secretory glycoprotein found primarily in apocrine tissues including the breast and salivary glands. With largely unknown functions, PIP has been implicated in breast cancer and metastasis, host defense processes and T lymphocyte apoptosis. To begin to address PIP function in vivo, we generated the PIP null mouse...
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