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Article

Gene Expression Signature for Biliary Atresia and a Role for Interleukin-8 in Pathogenesis of Experimental Disease

4 Feb 2014

Abstract excerpt

UNLABELLED: Biliary atresia (BA) is a progressive fibroinflammatory obstruction of extrahepatic bile ducts that presents as neonatal cholestasis. Due to the overlap in clinical, biochemical, and histological features with other causes of cholestasis, the diagnosis requires an intraoperative cholangiogram. Thus, we determined whether diseased livers express a gene expression signature unique to BA. Applying...

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PMID: 24493287
DOI: 10.1002/hep.27045

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