Article

Lamins regulate nuclear mechanics and shape to control glioblastoma cell proliferation, migration and invasion

2024-10-01

Abstract excerpt

Glioblastoma (GBM) is known as the most aggressive brain tumor and is characterized by a high heterogeneity and a median patient survival time around 15 months. Phenotyping based on cell mechanics is increasingly recognized as a potential prognostic marker for tumor aggressiveness. We have previously shown that cell and nuclear mechanical properties vary between different grades of gliomas and may be used to diffe...

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Identifiers and source

Literature Corpus work: 435da64d-6a73-507a-8630-fc11783e6bb6
DOI: 10.1101/2024.09.30.615792

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