Article

Intermediate filaments promote glioblastoma cell invasion by controlling cell deformability and mechanosensitive gene expression

2023-06-29

Abstract excerpt

<title>Abstract</title> <p>Cancer invasion turns a locally growing tumour into a live-threatening disease. Unravelling the molecular signature of invasive cells and their mechanisms of invasion is essential to identify therapeutic targets. While the cytoskeleton is known to support cell mechanical properties required for invasion, the role of intermediate filaments (IFs) is often overlooked. Here we investigated...

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Literature Corpus work: a1d91524-694f-5160-b84b-6ed688ee5b4e
DOI: 10.21203/rs.3.rs-2828066/v1

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