Article

Cell migration simulator-based biomarkers for glioblastoma

2023-02-24

Abstract excerpt

Glioblastoma is the most aggressive malignant brain tumor with poor survival due to its invasive nature driven by cell migration, with unclear linkage to transcriptomic information. Here, we applied a physics-based motor-clutch model, a cell migration simulator (CMS), to parameterize the migration of glioblastoma cells and define physical biomarkers on a patient-by-patient basis. We reduced the 11-dimensional para...

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Literature Corpus work: bfb3a1eb-16bf-51f1-9754-f0cbaba67a97
DOI: 10.1101/2023.02.24.529880

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