Article

Chronic exercise protects against the progression of renal cyst growth and dysfunction in rats with polycystic kidney disease

2021-03-12

Abstract excerpt

<h4>Introduction</h4> Polycystic kidney disease (PKD) is a genetic disorder characterized by the progressive enlargement of renal epithelial cysts and renal dysfunction. Previous studies have reported the beneficial effects of chronic exercise on chronic kidney disease. However, the effects of chronic exercise have not been fully examined in PKD patients or models. The effects of chronic exercise on the progressi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 435b9284-d274-5c2b-89a4-1238dee75828
DOI: 10.1101/2021.03.11.434857

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Chronic exercise protects against the progression of renal cyst growth and dysfunction in rats with polycystic kidney diseaseDOI 10.1101/2021.03.11.434857Read

Apelin inhibits cyst growth and improves kidney function in mice with polycystic kidney diseaseSemantic proximity Read

Autosomic dominant polycystic kidney disease and metformin: Old knowledge and new insights on retarding progression of chronic kidney disease.Semantic proximity Read

Autosomal dominant polycystic kidney disease: Disrupted pathways and potential therapeutic interventions.Semantic proximity Read

Metformin improves relevant disease parameters in an autosomal dominant polycystic kidney disease mouse model.Semantic proximity Read

Translational research in ADPKD: lessons from animal models.Semantic proximity Read

Autosomal dominant polycystic kidney disease and pioglitazone for its therapy: a comprehensive review with an emphasis on the molecular pathogenesis and pharmacological aspects.Semantic proximity Read

Mechanisms of progression of chronic kidney disease.Semantic proximity Read

Therapeutic advances in the treatment of polycystic kidney disease.Semantic proximity Read

c-Jun N-terminal kinase (JNK) signaling contributes to cystic burden in polycystic kidney diseaseSemantic proximity Read

Ablation of the Renal Tubular Gluconeogenic Enzyme PCK1 Drives AKI-to-CKD Transition by Negatively Regulating the TGF-β/Smad3 Signaling PathwaySemantic proximity Read

Time-Restricted Feeding Attenuates Kidney Damage and Preserves Renal Function in Mouse Model of Chronic Kidney DiseaseSemantic proximity Read

Inhibition of Aerobic Glycolysis Attenuates Disease Progression in Polycystic Kidney Disease.Semantic proximity Read