Article
Mechanisms of progression of chronic kidney disease.
Pediatric nephrology (Berlin, Germany) - 1 Dec 2007
Fogo Agnes B
Abstract excerpt
Chronic kidney disease (CKD) occurs in all age groups, including children. Regardless of the underlying cause, CKD is characterized by progressive scarring that ultimately affects all structures of the kidney. The relentless progression of CKD is postulated to result from a self-perpetuating vicious cycle of fibrosis activated after initial injury. We will review possible mechanisms of progressive renal damage,...
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