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Article

Autosomal dominant polycystic kidney disease: Disrupted pathways and potential therapeutic interventions.

Journal of cellular physiology - 1 Aug 2019

Malekshahabi Talieh, Khoshdel Rad Niloofar, Serra Andreas L, Moghadasali Reza

Abstract excerpt

Autosomal dominant polycystic kidney disease (ADPKD) is a monogenic inherited renal cystic disease that occurs in different races worldwide. It is characterized by the development of a multitude of renal cysts, which leads to massive enlargement of the kidney and often to renal failure in adulthood. ADPKD is caused by a mutation in PKD1 or PKD2 genes encoding the proteins polycystin-1 and polycystin-2,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30644092
DOI: 10.1002/jcp.28094
PMCID: PMC13484091

Genes

PKD1
PKD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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