Article

Disclosing the actual efficiency of G-quadruplex-DNA–disrupting small molecules

2020-11-16

Abstract excerpt

The quest for small molecules that avidly bind to G-quadruplex-DNA (G4-DNA, or G4), so called G4-ligands, has invigorated the G4 research field from its very inception. Massive efforts have been invested to i - screen or design G4-ligands, ii - evaluate their G4-interacting properties in vitro through a series of now widely accepted and routinely implemented assays, and iii - use them as unique chemical biolog...

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Literature Corpus work: 432fe88c-91f7-56ac-9eba-d9ee66a7640c
DOI: 10.1101/2020.11.16.382176

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