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Towards customized studies of G-quadruplex DNA structures in live cells

2021-04-07

Abstract excerpt

G-quadruplex (G4) DNA structures are implicated in central biological processes and are considered promising therapeutic targets because of their links to human diseases such as cancer. However, functional details of how, when, and why G4 DNA structures form in vivo are largely missing leaving a knowledge gap that requires tailored chemical biology studies in relevant live-cell model systems. Towards this end, we...

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Identifiers and source

Literature Corpus work
e8dd6469-b0d9-55c3-b110-e221ffe4d9c8
DOI
10.1101/2021.04.07.438780
Open publication

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Towards customized studies of G-quadruplex DNA structures in live cellsDOI 10.1101/2021.04.07.438780
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