Article

Massively multiplex single-cell Hi-C

2016-07-23

Abstract excerpt

We present combinatorial single cell Hi-C, a novel method that leverages combinatorial cellular indexing to measure chromosome conformation in large numbers of single cells. In this proof-of-concept, we generate and sequence combinatorial single cell Hi-C libraries for two mouse and four human cell types, comprising a total of 9,316 single cells across 5 experiments. We demonstrate the utility of single-cell Hi-C...

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Literature Corpus work: 432227b6-2993-5fc2-b058-6521f31ce319
DOI: 10.1101/065052

Open publication

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