Article

Optical Genome and Epigenome Mapping of Clear Cell Renal Cell Carcinoma

2022-10-12

Abstract excerpt

<h4>ABSTRACT</h4> Cancer cells display complex genomic aberrations that include large-scale genetic rearrangements and epigenetic modulation that are not easily characterized by short-read sequencing. We present a method for simultaneous profiling of long-range genetic/epigenetic changes in matched cancer samples. Clear cell renal cell carcinoma (ccRCC) is the most common subtype of kidney cancer. Most ccRCC case...

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Literature Corpus work: 43207c25-b13a-5c53-bccb-9e085b2bb255
DOI: 10.1101/2022.10.11.511152

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