Article

Whole genome sequencing refines stratification and therapy of patients with clear cell renal cell carcinoma

2023-12-06

Abstract excerpt

<title>Abstract</title> <p><bold>Clear cell renal cell carcinoma (ccRCC) is the most common form of kidney cancer, but a comprehensive description of its genomic landscape is lacking. We report the whole genome sequencing of 778 ccRCC patients enrolled in the 100,000 Genomes Project, providing the most detailed somatic mutational landscape to date. We identify new driver genes, which as well as emphasising the ma...

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Literature Corpus work: 07a95887-e5ef-5d58-b5f0-fcf1fcfde1e0
DOI: 10.21203/rs.3.rs-3675752/v1

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