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Article

Multilayer-omics analysis of renal cell carcinoma, including the whole exome, methylome and transcriptome.

International journal of cancer - 15 Sept 2014

Arai Eri, Sakamoto Hiromi, Ichikawa Hitoshi, Totsuka Hirohiko, Chiku Suenori, Gotoh Masahiro, Mori Taisuke, Nakatani Tamao, Ohnami Sumiko, Nakagawa Tohru, Fujimoto Hiroyuki, Wang Linghua, Aburatani Hiroyuki, Yoshida Teruhiko, Kanai Yae

Abstract excerpt

The aim of this study was to identify pathways that have a significant impact during renal carcinogenesis. Sixty-seven paired samples of both noncancerous renal cortex tissue and cancerous tissue from patients with clear cell renal cell carcinomas (RCCs) were subjected to whole-exome, methylome and transcriptome analyses using Agilent SureSelect All Exon capture followed by sequencing on an Illumina HiSeq 2000...

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Share to Carcinoma, Renal Cell
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Kidney Neoplasms

Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 24504440
DOI: 10.1002/ijc.28768
PMCID: PMC4235299

Genes

ABCA13
CCNC
CDK8
ERC2
MACF1
MED12
MTOR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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