Article
Genomic Profiling and Molecular Characterization of Clear Cell Renal Cell Carcinoma.
Current oncology (Toronto, Ont.) - 20 Oct 2023
Pezzicoli Gaetano, Ciciriello Federica, Musci Vittoria, Salonne Francesco, Ragno Anna, Rizzo Mimma
Abstract excerpt
Clear cell renal cell carcinoma (ccRCC) treatment has undergone three major paradigm shifts in recent years, first with the introduction of molecular targeted therapies, then with immune checkpoint inhibitors, and, more recently, with immune-based combinations. However, to date, molecular predictors of response to targeted agents have not been identified for ccRCC. The WHO 2022 classification of renal neoplasms...
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