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Contrasting Features of Papillary and Chromophobe Renal Cell Carcinoma Revealed by Whole-Genome Sequencing.

Molecular cancer research : MCR - 4 May 2026

Culliford Richard, Mills Charlie, Chubb Daniel, Kinnersley Ben, Sud Amit, Cornish Alex J, Browning Lisa, Lawrence Samuel E D, Bentham Robert, Frangou Anna, Gruber Andreas J, Litchfield Kevin, Wedge David C, Larkin James, Turajlic Samra, Houlston Richard S

Abstract excerpt

The identification of cancer drivers is a cornerstone to the delivery of precision oncology. So far, sequencing of renal cell cancer (RCC) has largely been confined to the clear cell subtype of RCC. In contrast, sequencing analyses of the less common forms of RCC, papillary RCC (pRCC) and chromophobe RCC (ChRCC), have so far been limited. We analyzed whole-genome sequencing data on 164 tumor-normal pairs from the...

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Identifiers

PMID: 41563788
DOI: 10.1158/1541-7786.MCR-25-0616
PMCID: PMC13136883

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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