Article
Characterization of long non-coding RNA transcriptome in clear-cell renal cell carcinoma by next-generation deep sequencing.
Molecular oncology - 1 Jan 2015
Malouf Gabriel G, Zhang Jianping, Yuan Ying, Compérat Eva, Rouprêt Morgan, Cussenot Olivier, Chen Yunxin, Thompson Erika J, Tannir Nizar M, Weinstein John N, Valero Vicente, Khayat David, Spano Jean-Philippe, Su Xiaoping
Abstract excerpt
INTRODUCTION: Long non-coding RNA (lncRNA) have proven to play key roles in cell physiology from nuclear organization and epigenetic remodeling to post-transcriptional regulation. Last decade, gene expression based-classifications have been developed in clear-cell renal cell carcinoma (ccRCC) to identify distinct subtypes of disease and predict patient's outcome. However, there are no current lncRNA comprehensive...
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