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Article

Epigenomics of clear cell renal cell carcinoma: mechanisms and potential use in molecular pathology.

1 Feb 2016

Abstract excerpt

Clear cell renal cell carcinoma (ccRCC) is one frequent form of urologic malignancy with numerous genetic and epigenetic alterations. This review summarizes the recent major findings of epigenetic alterations including DNA methylation, histone modifications, microRNAs and recently identified long noncoding RNAs in the development and progression of ccRCC. These epigenetic profilings can provide a promising means...

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PMID: 27041930
DOI: 10.3978/j.issn.1000-9604.2016.02.09

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