Article

Temporal evolution of inflammation and neurodegeneration with alpha-synuclein propagation in Parkinson’s disease mouse model

2021-02-26

Abstract excerpt

Alpha-synuclein (αSyn) propagation has been determined to play a key role in the pathomechanism of Parkinson’s disease (PD), but neurodegeneration and the involvement of inflammation in its pathologic progression are yet to be well understood with regard to temporal relationship. In this study, by means of PD mouse model injected with intrastriatal αSyn preformed fibril (PFF), the temporal evolution of αSyn propag...

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Literature Corpus work: 42e5eb75-1815-54b0-a095-4cff1fac0d67
DOI: 10.21203/rs.3.rs-250127/v1

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