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Relationship among α‑synuclein, aging and inflammation in Parkinson's disease (Review)

21 Nov 2023

Abstract excerpt

Parkinson's disease (PD) is a common neurodegenerative pathology whose major clinical symptoms are movement disorders. The main pathological characteristics of PD are the selective death of dopaminergic (DA) neurons in the pars compacta of the substantia nigra and the presence of Lewy bodies containing α-synuclein (α-Syn) within these neurons. PD is associated with numerous risk factors, including environmental...

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PMID: 38125364
DOI: 10.3892/etm.2023.12311

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