Article

A-TWAS: An aggregated transcriptome-wide association study model incorporating multiple Bayesian priors

2025-01-28

Abstract excerpt

<h4>Motivation</h4> Transcriptome-wide association study (TWAS) is a significant methodology utilized for identifying associations between genes and diseases by integrating transcriptome and genome-wide association studies (GWAS) data. The approach has been successful in pinpointing risk genes for various diseases, including Alzheimer’s disease, schizophrenia, and different types of cancers. TWAS typically involv...

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Literature Corpus work: 42c27d86-b671-5e8f-bfbd-7b5480be6f08
DOI: 10.1101/2025.01.27.635054

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