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Article

MOSTWAS: Multi-Omic Strategies for Transcriptome-Wide Association Studies.

PLoS genetics - 1 Mar 2021

Bhattacharya Arjun, Li Yun, Love Michael I

Abstract excerpt

Traditional predictive models for transcriptome-wide association studies (TWAS) consider only single nucleotide polymorphisms (SNPs) local to genes of interest and perform parameter shrinkage with a regularization process. These approaches ignore the effect of distal-SNPs or other molecular effects underlying the SNP-gene association. Here, we outline multi-omics strategies for transcriptome imputation from...

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PMID: 33684137
DOI: 10.1371/journal.pgen.1009398
PMCID: PMC7971899

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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