Article

MOSTWAS: Multi-Omic Strategies for Transcriptome-Wide Association Studies

2020-04-18

Abstract excerpt

<h4>ABSTRACT</h4> Traditional predictive models for transcriptome-wide association studies (TWAS) consider only single nucleotide polymorphisms (SNPs) local to genes of interest and perform parameter shrinkage with a regularization process. These approaches ignore the effect of distal-SNPs or other molecular effects underlying the SNP-gene association. Here, we outline multi-omics strategies for transcriptome imp...

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Literature Corpus work: b7b2b36b-bb4f-5b86-aab3-3833e876068c
DOI: 10.1101/2020.04.17.047225

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