Article

TIGAR-V2: Efficient TWAS Tool with Nonparametric Bayesian eQTL Weights of 49 Tissue Types from GTEx V8

2021-07-16

Abstract excerpt

Standard Transcriptome-Wide Association Study (TWAS) methods first train gene expression prediction models using reference transcriptomic data, and then test the association between the predicted genetically regulated gene expression and phenotype of interest. Most existing TWAS tools require cumbersome preparation of genotype input files and extra coding to enable parallel computation. To improve the efficiency o...

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Literature Corpus work: 9a68560b-37c3-5b82-9437-7f6e7770821c
DOI: 10.1101/2021.07.16.452700

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