Article

The vascular gene Apold1 is dispensable for normal development but controls angiogenesis under pathological conditions

2022-12-13

Abstract excerpt

The molecular mechanisms of angiogenesis have been intensely studied, but many genes that control endothelial behavior and fate still need to be described. Here, we characterize the role of Apold1 (Apolipoprotein L domain containing 1) in angiogenesis in vivo and in vitro. Single-cell analyses reveal that - across tissues - the expression of Apold1 is restricted to the vasculature, and that Apold1 expression in en...

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Literature Corpus work: 4245521d-6069-5085-863c-1a5f908516e9
DOI: 10.21203/rs.3.rs-2361644/v1

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