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Article

Low-Density Lipoprotein Receptor-Related Protein-1 Signaling in Angiogenesis

22 May 2017

Abstract excerpt

Low-density lipoprotein receptor-related protein-1 (LRP1) plays multifunctional roles in lipid homeostasis, signaling transduction, and endocytosis. It has been recognized as an endocytic receptor for many ligands and is involved in the signaling pathways of many growth factors or cytokines. Dysregulation of LRP1-dependent signaling events contributes to the development of pathophysiologic processes such as...

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PMID: 28589128
DOI: 10.3389/fcvm.2017.00034

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