Article
Vascular development: genetic mechanisms and links to vascular disease.
Current topics in developmental biology - 1 Jan 2010
Chappell John C, Bautch Victoria L
Abstract excerpt
Vertebrate development depends on the formation of intricate vascular networks at numerous sites and in precise patterns; these vascular networks supply oxygen and nutrients to the rapidly expanding tissues of the embryo. Embryonic blood vessels are composed of endothelial cells and pericytes that organize and expand into highly branched conduits. Proper development of the vasculature requires heterogeneity in...
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