Article

The disappointment centre of the brain gets exciting: A systematic review of habenula dysfunction in depression

2024-04-19

Abstract excerpt

<h4>Background</h4> The habenula is an epithalamic brain structure that acts as a neuroanatomical hub connecting the limbic forebrain to the major monoamine centres. Abnormal habenula activity is increasingly implicated in depression, with a surge in publications on this topic in the last 5 years. Direct stimulation of the habenula is sufficient to induce a depressive phenotype in rodents, suggesting a causative...

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Literature Corpus work: 421f5a30-cfd5-5803-9a0a-75056f2e8ea2
DOI: 10.1101/2024.04.15.589608

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