Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The habenular volume and PDE7A allelic polymorphism in major depressive disorder: preliminary findings.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Mar 2023

Aftanas Lyubomir I, Filimonova Elena A, Anisimenko Maksim S, Berdyugina Darya A, Rezakova Maria V, Simutkin German G, Bokhan Nikolay A, Ivanova Svetlana A, Danilenko Konstantin V, Lipina Tatiana V

Abstract excerpt

OBJECTIVES: The habenula is a brain structure implicated in depression, yet with unknown molecular mechanisms. Several phosphodiesterases (PDEs) have been associated with a risk of depression. Although the role of PDE7A in the brain is unknown, it has enriched expression in the medial habenula, suggesting that it may play a role in depression. METHODS: We analysed: (1) habenula volume assessed by 3-T magnetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Depressive Disorder, Major
Share to Magnetic Resonance Imaging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 35673941
DOI: 10.1080/15622975.2022.2086297

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The habenular volume and PDE7A allelic polymorphism in major depressive disorder: preliminary findings.PMID 35673941Read ↗

Exploratory imaging-genetics associations between habenula connectivity and symptom severity in major depressive disorder.Semantic proximity Read ↗

Transcriptomic profiling of the human habenula reveals a shared molecular architecture across mood disordersSemantic proximity Read ↗

The disappointment centre of the brain gets exciting: A systematic review of habenula dysfunction in depressionSemantic proximity Read ↗

Testing the Hypothesis of Habenula Hyperactivity in Depression: A Study Using Fractional Amplitude of Low-Frequency Fluctuation (fALFF)Semantic proximity Read ↗

The importance of identifying functional Val158Met polymorphism in catechol-O- Methyltransferase when assessing MRI-based volumetric measurements in major depressive disorder.Semantic proximity Read ↗

A rare variant in GPR156 associated with depression in a Mennonite pedigree causes habenula hyperactivity and stress sensitivity in mice.Semantic proximity Read ↗

Hippocampal volume and serotonin transporter polymorphism in major depressive disorderSemantic proximity Read ↗

Relationship between G1287A of the NET Gene Polymorphisms and Brain Volume in Major Depressive Disorder: A Voxel-Based MRI Study.Semantic proximity Read ↗

Thyroid hormone transporter genes and grey matter changes in patients with major depressive disorder and healthy controls.Semantic proximity Read ↗

A single-nucleotide polymorphism influences brain morphology in drug-naïve patients with major depressive disorderSemantic proximity Read ↗

Additive sex-specific influence of common non-synonymous DISC1 variants on amygdala, basal ganglia, and white cortical surface area in healthy young adults.Semantic proximity Read ↗

Multimodal neuroimaging changes and their behavioral, genetic, and neurotransmitter correlates in electroconvulsive therapy for major depressive disorderSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.