Article

Translational Evidence for Habenula’s Role in Human Addiction: A Scoping Review

2026-06-20

Abstract excerpt

<p>Addiction is a chronic, relapsing disorder comprising three stages: binge, withdrawal, and preoccupation. Preclinical evidence suggests that the habenula, a small epithalamic region, is involved across these stages and may contribute to long-term neuroadaptations in reward, stress, and control systems. Human research on the habenula in addiction is growing but remains fragmented. This scoping review synthesizes...

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Literature Corpus work: 7a182667-9a3b-5b90-bcca-e192180cbe40
DOI: 10.31234/osf.io/snyvc_v1

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