Article

Susceptibility of BAFF-var allele carriers to severe SLE with occurrence of lupus nephritis

2019-11-06

Abstract excerpt

<title>Abstract</title> <p>Background: Dysregulation of the B-cell activating factor (BAFF) system is involved in the pathogenesis of systemic lupus erythematosus (SLE). Increased serum concentrations of BAFF are related to lupus nephritis and disease activity among SLE patients. Recently, a variant of the BAFF-encoding gene, BAFF-var, was identified to be associated with autoimmune diseases, in particular SLE, a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 41f06ca9-e9e8-56eb-ba6d-c88175a36486
DOI: 10.21203/rs.2.13758/v3

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Susceptibility of BAFF-var allele carriers to severe SLE with occurrence of lupus nephritisDOI 10.21203/rs.2.13758/v3Read

Susceptibility of BAFF-var allele carriers to severe SLE with occurrence of lupus nephritis.Semantic proximity Read

Association of a rare variant of the TNFSF13B gene with susceptibility to Rheumatoid Arthritis and Systemic Lupus Erythematosus.Semantic proximity Read

High BAFF expression associated with active disease in systemic lupus erythematosus and relationship with rs9514828C>T polymorphism in TNFSF13B geneSemantic proximity Read

B-cell activating factor and related genetic variants in lupus related atherosclerosis.Semantic proximity Read

Increased levels of BAFF in patients with systemic lupus erythematosus are associated with acute-phase reactants, independent of BAFF genetics: a case-control study.Semantic proximity Read

B-cell activating factor promoter polymorphisms in egyptian patients with systemic lupus erythematosus.Semantic proximity Read

BAFF, APRIL and BAFFR on the pathogenesis of Immunoglobulin-A vasculitis.Semantic proximity Read

FYB gene polymorphisms are associated with susceptibility for systemic lupus erythemathosus (SLE).Semantic proximity Read

The H159Y Variant of the BAFF-R Gene (TNFRSF13C) Is Unrelated to the Risk of Developing Systemic Lupus Erythematosus and Sjögren's Disease in a Mexican Population.Semantic proximity Read

Overexpression of the Cytokine BAFF and Autoimmunity Risk.Semantic proximity Read

Association of variants in BAFF (rs9514828 and rs1041569) and BAFF-R (rs61756766) genes with the risk of chronic lymphocytic leukemia.Semantic proximity Read

CVID-Associated B Cell Activating Factor Receptor Variants Change Receptor Oligomerization, Ligand Binding and Signaling ResponsesSemantic proximity Read