Article
BAFF, APRIL and BAFFR on the pathogenesis of Immunoglobulin-A vasculitis.
Scientific reports - 1 Jun 2021
Prieto-Peña Diana, Genre Fernanda, Remuzgo-Martínez Sara, Pulito-Cueto Verónica, Atienza-Mateo Belén, Llorca Javier, Sevilla-Pérez Belén, Ortego-Centeno Norberto, Lera-Gómez Leticia, Leonardo María Teresa, Peñalba Ana, Narváez Javier, Martín-Penagos Luis, Rodrigo Emilio, Miranda-Filloy José A, Caminal-Montero Luis, Collado Paz, Pérez Javier Sánchez, de Argila Diego, Rubio Esteban, Luque Manuel León, Blanco-Madrigal Juan María, Galíndez-Agirregoikoa Eva, Gualillo Oreste, Martín Javier, Castañeda Santos, Blanco Ricardo, González-Gay Miguel A, López-Mejías Raquel
Abstract excerpt
BAFF, APRIL and BAFF-R are key proteins involved in the development of B-lymphocytes and autoimmunity. Additionally, BAFF, APRIL and BAFFR polymorphisms were associated with immune-mediated conditions, being BAFF GCTGT>A a shared insertion-deletion genetic variant for several autoimmune diseases. Accordingly, we assessed whether BAFF, APRIL and BAFFR represent novel genetic risk factors for Immunoglobulin-A...
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