Article
B-cell activating factor promoter polymorphisms in egyptian patients with systemic lupus erythematosus.
Annals of clinical and laboratory science - 1 Jan 2013
Zayed Rania A, Sheba Hala F, Abo Elazaem Mennat Allah K, Elsaadany Zainab A, Elmessery Lobna O, Mahmoud Jelan A, Abdel Rahman Dalia R, Abdou Faten R
Abstract excerpt
BACKGROUND: Systemic lupus erythematosus (SLE) is a heterogonous autoimmune disease involving most immune cells. Studies have revealed a number of cytokine pathways that play important roles in the disease process. Among these is B- cell activating factor (BAFF), which regulates B-cell maturation, survival, and function. OBJECTIVE: To study the association between BAFF promoter polymorphism and systemic lupus...
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