Article
Association of variants in BAFF (rs9514828 and rs1041569) and BAFF-R (rs61756766) genes with the risk of chronic lymphocytic leukemia.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Oct 2016
Jasek Monika, Bojarska-Junak Agnieszka, Wagner Marta, Sobczyński Maciej, Wołowiec Dariusz, Roliński Jacek, Karabon Lidia, Kuśnierczyk Piotr
Abstract excerpt
The B-cell activator factor (BAFF)/BAFF receptor (BAFF-R) axis seems to play an important role in the development and progression of chronic lymphocytic leukemia (CLL). Here, we investigated the association of eight single nucleotide polymorphisms (SNPs) in the BAFF (TNFSF13B) and BAFF-R (TNFRSF13C) genes with risk of sporadic CLL in a group of 439 CLL patients and 477 controls. We also examined the correlation...
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