Association of a rare variant of the TNFSF13B gene with susceptibility to Rheumatoid Arthritis and Systemic Lupus Erythematosus.

doi:10.1038/s41598-018-26573-4

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Article

Association of a rare variant of the TNFSF13B gene with susceptibility to Rheumatoid Arthritis and Systemic Lupus Erythematosus.

Scientific reports - 29 May 2018

González-Serna David, Ortiz-Fernández Lourdes, Vargas Sofía, García Antonio, Raya Enrique, Fernández-Gutierrez Benjamín, López-Longo Francisco Javier, Balsa Alejandro, González-Álvaro Isidoro, Narvaez Javier, Gómez-Vaquero Carmen, Sabio José Mario, García-Portales Rosa, González-Escribano María Francisca, Tolosa Carles, Carreira Patricia, Kiemeney Lambertus, Coenen Marieke J H, Witte Torsten, Schneider Matthias, González-Gay Miguel Ángel, Martín Javier

Abstract excerpt

A rare variant (BAFF-var) of the tumor necrosis factor superfamily 13b (TNFSF13B) gene has been recently associated with multiple sclerosis (MS) and systemic lupus erythematosus (SLE). The aim of this study was to investigate the association between TNFSF13B BAFF-var and susceptibility to rheumatoid arthritis (RA) and replicate that association in SLE. 6,218 RA patients, 2,575 SLE patients and 4,403 healthy...

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PMID: 29844438
DOI: 10.1038/s41598-018-26573-4
PMCID: PMC5974315

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