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Article

FYB gene polymorphisms are associated with susceptibility for systemic lupus erythemathosus (SLE).

Human immunology - 1 Aug 2013

Addobbati Catarina, Brandão Lucas André Cavalcanti, Guimarães Rafael Lima, Pancotto João Alexandre Trés, Donadi Eduardo Antônio, Crovella Sergio, Segat Ludovica, Sandrin-Garcia Paula

Abstract excerpt

Systemic Lupus Erythematosus (SLE) is a multifactorial autoimmune disease affecting different organs or systems. Several genes have been associated with SLE susceptibility so far. A previous study has reported, in SLE patients, a differential expression of Fyn Binding Protein gene (FYB), encoding for a protein participating in the T cells signaling cascade and in the interleukin-2A expression modulation. This...

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Identifiers

PMID: 23628395
DOI: 10.1016/j.humimm.2013.04.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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