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Article

Susceptibility of BAFF-var allele carriers to severe SLE with occurrence of lupus nephritis.

BMC nephrology - 21 Nov 2019

Friebus-Kardash Justa, Trendelenburg Marten, Eisenberger Ute, Ribi Camillo, Chizzolini Carlo, Huynh-Do Uyen, Lang Karl Sebastian, Wilde Benjamin, Kribben Andreas, Witzke Oliver, Dolff Sebastian, Hardt Cornelia

Abstract excerpt

BACKGROUND: Dysregulation of the B-cell activating factor (BAFF) system is involved in the pathogenesis of systemic lupus erythematosus (SLE). Increased serum concentrations of BAFF are related to lupus nephritis and disease activity among SLE patients. Recently, a variant of the BAFF-encoding gene, BAFF-var, was identified to be associated with autoimmune diseases, in particular SLE, and to promote the...

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Identifiers

PMID: 31752784
DOI: 10.1186/s12882-019-1623-4
PMCID: PMC6873527

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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