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Increased levels of BAFF in patients with systemic lupus erythematosus are associated with acute-phase reactants, independent of BAFF genetics: a case-control study.

Rheumatology (Oxford, England) - 1 Dec 2011

Eilertsen Gro Ø, Van Ghelue Marijke, Strand Harald, Nossent Johannes C

Abstract excerpt

OBJECTIVES: To determine whether increased levels of B-cell activating factor (BAFF) in patients with SLE are due to disease activity or genetic variations in the promoter region of the BAFF gene and BAFF gene expression. METHODS: The case-control study included 101 SLE patients and 111 healthy controls. Five single nucleotide polymorphisms (SNPs) in the BAFF promoter region were investigated by melting point...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21984763
DOI: 10.1093/rheumatology/ker282

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