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Article

The H159Y Variant of the BAFF-R Gene (TNFRSF13C) Is Unrelated to the Risk of Developing Systemic Lupus Erythematosus and Sjögren's Disease in a Mexican Population.

International journal of molecular sciences - 10 Jan 2026

Borunda-Calderón Itzel María, Corona-Angeles Jazz Alan, Espinoza-García Noemí, Marín-Rosales Miguel, Salazar-Camarena Diana Celeste, Oregon-Romero Edith, Morales-Zambrano Ramsés Alejandro, Palafox-Sánchez Claudia Azucena

Abstract excerpt

Systemic Lupus Erythematosus (SLE) and primary Sjögren's Disease (SjD) are autoimmune diseases characterized by the presence of autoantibodies that lead to damage in healthy tissues. The production of autoantibodies requires the activation and differentiation of B-lymphocytes into plasma cells. To achieve this effect, BAFF (B-lymphocyte activating factor), APRIL (A proliferation-inducing ligand), and their...

Topics

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B-Cell Activating Factor
Case-Control Studies
Gene Frequency
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lupus Erythematosus, Systemic

Polymorphism, Single Nucleotide

Sjogren's Syndrome

Source

Open in PubMed Open full text

Identifiers

PMID: 41596376
DOI: 10.3390/ijms27020726
PMCID: PMC12841347

Genes

TNFRSF13C

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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The H159Y Variant of the BAFF-R Gene (TNFRSF13C) Is Unrelated to the Risk of Developing Systemic Lupus Erythematosus and Sjögren's Disease in a Mexican Population.PMID 41596376Read ↗

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