Back to search

Article

Immunogenomic landscape of hematological malignancies

2019-04-26

Abstract excerpt

<h4>SUMMARY</h4> Understanding factors that shape the immune landscape across hematological malignancies is essential for immunotherapy development. Here, we integrated over 8,000 transcriptomes and over 1,000 samples with multilevel genomic data of hematological cancers to investigate how immunological features are linked to cancer subtypes, genetic and epigenetic alterations, and patient survival. Infiltration...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
c2d11d9d-5603-5e15-94f3-0e4e94dd495e
DOI
10.1101/618918
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Immunogenomic landscape of hematological malignanciesDOI 10.1101/618918
Immunogenomic Landscape of Hematological Malignancies.Semantic proximity
The Immune Landscape of CancerSemantic proximity
A Pan-cancer Landscape of Interactions between Solid Tumors and Infiltrating Immune Cell PopulationsSemantic proximity
Immune Contexture, Immunoscore, and Malignant Cell Molecular Subgroups for Prognostic and Theranostic Classifications of Cancers.Semantic proximity
Genomic alterations underlying immune privilege in malignant lymphomasSemantic proximity
A Single-Cell Tumor Immune Atlas for Precision OncologySemantic proximity
Immune cell landscape reveals 5 immune-related subtypes and molecular characteristics with prognostic and therapeutic implications in pan-cancer.Semantic proximity
Genomic profiling for clinical decision making in lymphoid neoplasmsSemantic proximity
A single-cell pan-cancer analysis to show the variability of tumor-infiltrating myeloid cells in immune checkpoint blockadeSemantic proximity
Immunogenomic pan-cancer landscape reveals immune escape mechanisms and immunoediting histories.Semantic proximity
Tumoral immune microenvironment profiling in B-cell non-Hodgkin lymphoma stratifies patients in different prognostic groups.Semantic proximity
Immune-related pan-cancer gene expression signatures of patient survival revealed by NanoString-based analysesSemantic proximity
Select a neighboring publication to make it the new centre.