Article

MEGA dPCR reveals chromosomal aberrations, NHEJ precise repair, recurrent nuclease cleavage and DSB half-life

2024-06-26

Abstract excerpt

<title>Abstract</title> <p>Advances in designer DNA editors, such as programmable nucleases, PASTE, Prime, and base editors, have recently proved their therapeutic value and potential to treat genetic disorders. However, a comprehensive understanding of their cellular activities is essential for improving their editing efficiency and ensuring a safe clinical translation of cell and gene therapies. A myriad of tec...

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Literature Corpus work: 41d1143a-15cf-561a-987d-7fdc7fcf4ef7
DOI: 10.21203/rs.3.rs-4577114/v1

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MEGA dPCR reveals chromosomal aberrations, NHEJ precise repair, recurrent nuclease cleavage and DSB half-lifeDOI 10.21203/rs.3.rs-4577114/v1Read

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