Article

Cardiolipin dynamics promote membrane remodeling by mitochondrial OPA1

2024-05-23

Abstract excerpt

Cardiolipin (CL) is a mitochondria-specific phospholipid that forms heterotypic interactions with membrane-shaping proteins and regulates the dynamic remodeling and function of mitochondria. However, the precise mechanisms through which CL influences mitochondrial morphology are not well understood. In this study, employing molecular dynamics (MD) simulations, we determined that CL molecules extensively engage wit...

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Literature Corpus work: 415ae2ab-4e90-5867-9a3a-560747429641
DOI: 10.1101/2024.05.21.595226

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