Article
Mitochondrial dynamics and disease, OPA1.
Biochimica et biophysica acta - 1 Jan 2000
Olichon Aurélien, Guillou Emmanuelle, Delettre Cécile, Landes Thomas, Arnauné-Pelloquin Laetitia, Emorine Laurent J, Mils Valérie, Daloyau Marlène, Hamel Christian, Amati-Bonneau Patrizia, Bonneau Dominique, Reynier Pascal, Lenaers Guy, Belenguer Pascale
Abstract excerpt
The mitochondria are dynamic organelles that constantly fuse and divide. An equilibrium between fusion and fission controls the morphology of the mitochondria, which appear as dots or elongated tubules depending the prevailing force. Characterization of the components of the fission and fusion machineries has progressed considerably, and the emerging question now is what role mitochondrial dynamics play in...
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