Article

SOX transcription factors direct TCF-independent WNT/beta-catenin transcription

2021-08-26

Abstract excerpt

<h4>ABSTRACT</h4> WNT/ß-catenin signaling regulates gene expression across numerous biological contexts including development, stem cell homeostasis and tissue regeneration, and dysregulation of this pathway has been implicated in many diseases including cancer. One fundamental question is how distinct WNT target genes are activated in a context-specific manner, given the dogma that most, if not all, WNT/ß-cateni...

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Literature Corpus work: 4150b5ad-e6d3-5e38-a122-d52eb3f9e7f9
DOI: 10.1101/2021.08.25.457694

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