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Enhancer pioneering activity of Wnt/β-catenin signaling

2026-06-12

Abstract excerpt

Wnt/β-catenin signaling is widely understood as a molecular switch that activates preprogrammed regulatory states. Whether it also actively reshapes chromatin to establish those states has remained unclear. To address this, we performed time-resolved ATAC-seq and CUT&RUN analyses in HEK293T cells and monitored β-catenin-dependent changes in chromatin accessibility and complex assembly following pathway activation....

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Identifiers and source

Literature Corpus work
98067eab-6960-541a-838a-3e97f271ed33
DOI
10.64898/2026.06.12.731851
Open publication

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Enhancer pioneering activity of Wnt/β-catenin signalingDOI 10.64898/2026.06.12.731851
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