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Article

Distinct Transcriptional Programs Underlie Sox9 Regulation of the Mammalian Chondrocyte

1 Jul 2015

Abstract excerpt

Sox9 encodes an essential transcriptional regulator of chondrocyte specification and differentiation. When Sox9 nuclear activity was compared with markers of chromatin organization and transcriptional activity in primary chondrocytes, we identified two distinct categories of target association. Class I sites cluster around the transcriptional start sites of highly expressed genes with no chondrocyte-specific...

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PMID: 26146088
DOI: 10.1016/j.celrep.2015.06.013

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