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Article

Sox proteins: regulators of cell fate specification and differentiation

1 Oct 2013

Abstract excerpt

Sox transcription factors play widespread roles during development; however, their versatile funtions have a relatively simple basis: the binding of a Sox protein alone to DNA does not elicit transcriptional activation or repression, but requires binding of a partner transcription factor to an adjacent site on the DNA. Thus, the activity of a Sox protein is dependent upon the identity of its partner factor and...

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PMID: 24086078
DOI: 10.1242/dev.091793

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