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Article

HMGXB4 Targets <i>Sleeping Beauty</i> Transposition to Vertebrate Germinal Stem Cells

2020-06-15

Abstract excerpt

Transposons are parasitic genetic elements that frequently hijack key cellular processes of the host. HMGXB4 is a Wnt signalling-associated HMG-box protein, previously identified as a transcriptional regulating host factor of Sleeping Beauty (SB) transposition. Here, we establish that HMGXB4 is highly expressed from the zygote stage, and declines after transcriptional genome activation. Nevertheless, HMGXB4 is ac...

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Literature Corpus work
df652c5c-7a35-5499-84ac-bf4a2ee3082c
DOI
10.1101/2020.06.15.145656
Open publication

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HMGXB4 Targets <i>Sleeping Beauty</i> Transposition to Vertebrate Germinal Stem CellsDOI 10.1101/2020.06.15.145656
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