Article

On prs for complex polygenic trait prediction

2018-10-19

Abstract excerpt

Polygenic risk score (PRS) is the state-of-art prediction method for complex traits using summary level data from discovery genome-wide association studies (GWAS). The PRS, as its name suggests, is designed for polygenic traits by aggregating small genetic effects from a large number of causal SNPs and thus is viewed as a powerful method for predicting complex polygenic traits by the genetics community. However, o...

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Literature Corpus work: 413ffb19-00c8-5a57-9675-1edb8e36f30b
DOI: 10.1101/447797

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