Article

The role of endogenous inhibitors of nitric oxide on glucose homeostasis

2015-01-01

Abstract excerpt

Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthases. ADMA is metabolised by dimethylarginine dimethylaminohydrolase (DDAH) of which there are two isoforms with the same catalytic activity but different tissue expression patterns. Clinically ADMA is relevant as increased levels are seen in multiple pathologies, most notably cardiovascular disease and renal disease. Recent studies...

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Literature Corpus work: 4125b498-7eea-5c5d-9915-671daccd1eb7
DOI: 10.25560/24777

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